Interferon-β Modulates the Innate Immune Response against Glioblastoma Initiating Cells.

Immunotherapy targeting glioblastoma initiating cells (GIC) is considered a promising strategy. However, GIC are prone to evade immune response and there is a need for potent adjuvants. IFN-β might enhance the immune response and here we define its net effect on the innate immunogenicity of GIC. The...

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Bibliographic Details
Main Authors: Fabian Wolpert, Caroline Happold, Guido Reifenberger, Ana-Maria Florea, René Deenen, Patrick Roth, Marian Christoph Neidert, Katrin Lamszus, Manfred Westphal, Michael Weller, Günter Eisele
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4595134?pdf=render