Anterograde Tracing From the Göttingen Minipig Motor and Prefrontal Cortex Displays a Topographic Subthalamic and Striatal Axonal Termination Pattern Comparable to Previous Findings in Primates

Background: Deep brain stimulation (DBS) of the dorsal subthalamic nucleus (STN) is a validated neurosurgical treatment of Parkinson’s Disease (PD). To investigate the mechanism of action, including potential DBS induced neuroplasticity, we have previously used a minipig model of Parkinson’s Disease...

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Detalhes bibliográficos
Main Authors: Johannes Bech Steinmüller, Carsten Reidies Bjarkam, Dariusz Orlowski, Jens Christian Hedemann Sørensen, Andreas Nørgaard Glud
Formato: Artigo
Idioma:English
Publicado em: Frontiers Media S.A. 2021-11-01
Colecção:Frontiers in Neural Circuits
Assuntos:
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fncir.2021.716145/full