Decreased granzyme-B expression in CD11c+CD8+ T cells associated with disease progression in patients with HBV-related hepatocellular carcinoma

Decreased granzyme-B expression in CD11c+CD8+ T cells associated with disease progression in patients with HBV-related hepatocellular carcinoma

IntroductionCD11c+CD8+ T cells are an unconventional CD8+ T cell subset that exerts antiviral activity in infectious diseases. However, its characteristics in hepatocellular carcinoma (HCC) have not been elucidated.MethodsTwenty-six patients with hepatitis B virus (HBV)-related HCC and 25 healthy co...

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Bibliographic Details
Main Authors: Lin Gao, Zhixian Hong, Guanglin Lei, An-Liang Guo, Fu-Sheng Wang, Yan-Mei Jiao, Junliang Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
CD11c
CD8 T cells
hepatocellular carcinoma
hepatitis B virus
anti-tumor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1107483/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1107483/full

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