Optogenetic stimulation of the brainstem dorsal motor nucleus ameliorates acute pancreatitis

Optogenetic stimulation of the brainstem dorsal motor nucleus ameliorates acute pancreatitis

IntroductionInflammation is an inherently self-amplifying process, resulting in progressive tissue damage when unresolved. A brake on this positive feedback system is provided by the nervous system which has evolved to detect inflammatory signals and respond by activating anti-inflammatory processes...

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Bibliographic Details
Main Authors: Dane A. Thompson, Tea Tsaava, Arvind Rishi, Sandeep Nadella, Lopa Mishra, David A. Tuveson, Valentin A. Pavlov, Michael Brines, Kevin J. Tracey, Sangeeta S. Chavan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
acute pancreatitis
dorsal motor nucleus
vagus nerve
inflammation
cytokines
cholinergic anti-inflammatory pathway (CAP)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1166212/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1166212/full

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