CREBH determines the severity of sulpyrine-induced fatal shock.

CREBH determines the severity of sulpyrine-induced fatal shock.

Although the pyrazolone derivative sulpyrine is widely used as an antipyretic analgesic drug, side effects, including fatal shock, have been reported. However, the molecular mechanism underlying such a severe side effect is largely unclear. Here, we report that the transcription factor CREBH that is...

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Bibliographic Details
Main Authors: Naganori Kamiyama, Masahiro Yamamoto, Hiroyuki Saiga, Ji Su Ma, Jun Ohshima, Sakaaki Machimura, Miwa Sasai, Taishi Kimura, Yoshiyasu Ueda, Hisako Kayama, Kiyoshi Takeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3567110?pdf=render

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http://europepmc.org/articles/PMC3567110?pdf=render

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