Proteolysis-Targeting Chimera (PROTAC) Delivery into the Brain across the Blood-Brain Barrier

Drug development for neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease has challenging difficulties due to the pharmacokinetic impermeability based on the blood-brain barrier (BBB) as well as the blurriness of pharmacodynamic targets based on their...

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Bibliographic Details
Main Author: Toshihiko Tashima
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/12/3/43