New Mouse Model for Chronic Infections by Gram-Negative Bacteria Enabling the Study of Anti-Infective Efficacy and Host-Microbe Interactions

ABSTRACT Only a few, relatively cumbersome animal models enable long-term Gram-negative bacterial infections that mimic human situations, where untreated infections can last for weeks. Here, we describe a simple murine cutaneous abscess model that enables chronic or progressive infections, depending...

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Bibliographic Details
Main Authors: Daniel Pletzer, Sarah C. Mansour, Kelli Wuerth, Negin Rahanjam, Robert E. W. Hancock
Format: Article
Language:English
Published: American Society for Microbiology 2017-03-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00140-17