Design and Synthesis of New Pyrimidine-Quinolone Hybrids as Novel <i>h</i>LDHA Inhibitors
A battery of novel pyrimidine-quinolone hybrids was designed by docking scaffold replacement as lactate dehydrogenase A (<i>h</i>LDHA) inhibitors. Structures with different linkers between the pyrimidine and quinolone scaffolds (<b>10</b>-<b>21</b> and <b>24...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-06-01
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| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8247/15/7/792 |