Simultaneous two-photon imaging and two-photon optogenetics of cortical circuits in three dimensions

The simultaneous imaging and manipulating of neural activity could enable the functional dissection of neural circuits. Here we have combined two-photon optogenetics with simultaneous volumetric two-photon calcium imaging to measure and manipulate neural activity in mouse neocortex in vivo in three-...

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Bibliographic Details
Main Authors: Weijian Yang, Luis Carrillo-Reid, Yuki Bando, Darcy S Peterka, Rafael Yuste
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/32671