NUP-1 Is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions.

A unifying feature of eukaryotic nuclear organization is genome segregation into transcriptionally active euchromatin and transcriptionally repressed heterochromatin. In metazoa, lamin proteins preserve nuclear integrity and higher order heterochromatin organization at the nuclear periphery, but no...

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Main Authors: Kelly N DuBois, Sam Alsford, Jennifer M Holden, Johanna Buisson, Michal Swiderski, Jean-Mathieu Bart, Alexander V Ratushny, Yakun Wan, Philippe Bastin, J David Barry, Miguel Navarro, David Horn, John D Aitchison, Michael P Rout, Mark C Field
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3313915?pdf=render