Cell-cycle and apoptosis related and proteomics-based signaling pathways of human hepatoma Huh-7 cells treated by three currently used multi-RTK inhibitors

Cell-cycle and apoptosis related and proteomics-based signaling pathways of human hepatoma Huh-7 cells treated by three currently used multi-RTK inhibitors

Sorafenib, lenvatinib and regorafenib, the multi-RTK inhibitors with potent anti-angiogenesis effects, are currently therapeutic drugs generally recommended for the patients with advanced hepatocellular carcinoma (HCC). To date, however, there have been no published studies on the mechanism underlin...

Full description

Bibliographic Details
Main Authors: Xuejiao Ren, Qingning Zhang, Wenyan Guo, Lan Wang, Tao Wu, Wei Zhang, Ming Liu, Dezhi Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
cell cycle
cell apoptosis
proteomics
signal pathway
sorafenib
lenvatinib
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.944893/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.944893/full

Similar Items