Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry.
Numerous metabolic pathways have been implicated in diabetes-induced renal injury, yet few studies have utilized unbiased systems biology approaches for mapping the interconnectivity of diabetes-dysregulated proteins that are involved. We utilized a global, quantitative, differential proteomic appro...
Main Authors: | Jonathan M Starkey, Yingxin Zhao, Rovshan G Sadygov, Sigmund J Haidacher, Wanda S Lejeune, Nilay Dey, Bruce A Luxon, Maureen A Kane, Joseph L Napoli, Larry Denner, Ronald G Tilton |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-06-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2885420?pdf=render |
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