Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis.

Human alveolar macrophages display marked hypo-responsiveness to IFN-γ in both proteomic and gene expression analysis.

Alveolar macrophages (AM) perform a primary defense mechanism in the lung through phagocytosis of inhaled particles and microorganisms. AM are known to be relatively immunosuppressive consistent with the aim to limit alveolar inflammation and maintain effective gas exchange in the face of these cons...

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Bibliographic Details
Main Authors: Bonnie A Thiel, Kathleen C Lundberg, Daniela Schlatzer, Jessica Jarvela, Qing Li, Rachel Shaw, Scott M Reba, Shane Fletcher, Sara E Beckloff, Mark R Chance, W Henry Boom, Richard F Silver, Gurkan Bebek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295312&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0295312&type=printable

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