The role of fibroblast growth factor 1 and 2 on the pathological behavior of valve interstitial cells in a three-dimensional mechanically-conditioned model

The role of fibroblast growth factor 1 and 2 on the pathological behavior of valve interstitial cells in a three-dimensional mechanically-conditioned model

Abstract Background More than five million Americans suffer from heart valve disease annually, a condition that worsens cardiac function and gradually leads to heart failure if appropriate treatment is not performed on time. Currently no medication can cure heart valve disease, leaving surgical inte...

Full description

Bibliographic Details
Main Authors: Ngoc Thien Lam, Ishita Tandon, Kartik Balachandran
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Biological Engineering
Subjects:
Fibroblast growth factor
Fibroblast growth factor receptor
Valve interstitial cells
Three-dimensional cell culture
Mechanical stretch
Heart valve disease
Online Access:http://link.springer.com/article/10.1186/s13036-019-0168-1

Internet

http://link.springer.com/article/10.1186/s13036-019-0168-1

Similar Items