Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergies
Amrita Dosanjh,1 Kaitlyn P Lew21Pediatric Respiratory, San Diego, CA, USA; 2Brown University, Providence, RI, USAAbstract: The use of immunosuppressive treatments and their related gastrointestinal adverse effects have been implicated in the development of food allergic responses following transplan...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-07-01
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| Series: | Journal of Asthma and Allergy |
| Subjects: | |
| Online Access: | https://www.dovepress.com/blood-eosinophils-and-ige-levels-among-umbilical-cord-transplantation--peer-reviewed-article-JAA |
| _version_ | 1811201910246473728 |
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| author | Dosanjh A Lew KP |
| author_facet | Dosanjh A Lew KP |
| author_sort | Dosanjh A |
| collection | DOAJ |
| description | Amrita Dosanjh,1 Kaitlyn P Lew21Pediatric Respiratory, San Diego, CA, USA; 2Brown University, Providence, RI, USAAbstract: The use of immunosuppressive treatments and their related gastrointestinal adverse effects have been implicated in the development of food allergic responses following transplantation. There is limited information on the pathogenesis of the food allergic immune response among umbilical cord transplantation recipients. This study was conducted to identify a cohort of food allergic umbilical cord recipients in the literature. The literature was searched to systematically identify this cohort. Criteria for inclusion included umbilical cord transplantation, food allergic response, and reported laboratory data. Analysis of the laboratory data using the Pearson method revealed that there was a moderate negative correlation with a coefficient of r=−0.7016 and r2=−0.49 between peripheral eosinophilia and serum immunoglobulin E (IgE) levels. Future studies on a larger population are needed, but this study may help to elucidate possible cellular mechanisms involved in this response.Keywords: GVHD, tacrolimus, cord blood, stem cell |
| first_indexed | 2024-04-12T02:29:52Z |
| format | Article |
| id | doaj.art-5411e540db7d46ad9b6f65ea57aee664 |
| institution | Directory Open Access Journal |
| issn | 1178-6965 |
| language | English |
| last_indexed | 2024-04-12T02:29:52Z |
| publishDate | 2019-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Asthma and Allergy |
| spelling | doaj.art-5411e540db7d46ad9b6f65ea57aee6642022-12-22T03:51:51ZengDove Medical PressJournal of Asthma and Allergy1178-69652019-07-01Volume 1221321547552Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergiesDosanjh ALew KPAmrita Dosanjh,1 Kaitlyn P Lew21Pediatric Respiratory, San Diego, CA, USA; 2Brown University, Providence, RI, USAAbstract: The use of immunosuppressive treatments and their related gastrointestinal adverse effects have been implicated in the development of food allergic responses following transplantation. There is limited information on the pathogenesis of the food allergic immune response among umbilical cord transplantation recipients. This study was conducted to identify a cohort of food allergic umbilical cord recipients in the literature. The literature was searched to systematically identify this cohort. Criteria for inclusion included umbilical cord transplantation, food allergic response, and reported laboratory data. Analysis of the laboratory data using the Pearson method revealed that there was a moderate negative correlation with a coefficient of r=−0.7016 and r2=−0.49 between peripheral eosinophilia and serum immunoglobulin E (IgE) levels. Future studies on a larger population are needed, but this study may help to elucidate possible cellular mechanisms involved in this response.Keywords: GVHD, tacrolimus, cord blood, stem cellhttps://www.dovepress.com/blood-eosinophils-and-ige-levels-among-umbilical-cord-transplantation--peer-reviewed-article-JAAGVHDtacrolimuscord bloodstem cell |
| spellingShingle | Dosanjh A Lew KP Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergies Journal of Asthma and Allergy GVHD tacrolimus cord blood stem cell |
| title | Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergies |
| title_full | Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergies |
| title_fullStr | Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergies |
| title_full_unstemmed | Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergies |
| title_short | Blood eosinophils and IgE levels among umbilical cord transplantation recipients with food allergies |
| title_sort | blood eosinophils and ige levels among umbilical cord transplantation recipients with food allergies |
| topic | GVHD tacrolimus cord blood stem cell |
| url | https://www.dovepress.com/blood-eosinophils-and-ige-levels-among-umbilical-cord-transplantation--peer-reviewed-article-JAA |
| work_keys_str_mv | AT dosanjha bloodeosinophilsandigelevelsamongumbilicalcordtransplantationrecipientswithfoodallergies AT lewkp bloodeosinophilsandigelevelsamongumbilicalcordtransplantationrecipientswithfoodallergies |