Insufficient type I IFN immunity underlies life-threatening COVID-19 pneumonia

Insufficient type I IFN immunity underlies life-threatening COVID-19 pneumonia

We established the COVID Human Genetic Effort (www.covidhge.com) to discover the human genetic and immunological bases of the vast interindividual clinical variability between humans infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We found that about 3% of patients with l...

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Bibliographic Details
Main Authors: Bastard, Paul, Zhang, Qian, Cobat, Aurélie, Jouanguy, Emmanuelle, Zhang, Shen-Ying, Abel, Laurent, Casanova, Jean-Laurent
Format: Article
Language:English
Published: Académie des sciences 2021-02-01
Series:Comptes Rendus Biologies
Subjects:
Life-threatening COVID-19
Pneumonia
Type I interferons
Inborn errors of immunity
Autoantibodies
Online Access:https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.36/

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https://comptes-rendus.academie-sciences.fr/biologies/articles/10.5802/crbiol.36/

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