Activating transcription factor 4 drives the progression of diabetic cardiac fibrosis

Activating transcription factor 4 drives the progression of diabetic cardiac fibrosis

Abstract Aims Diabetic cardiomyopathy (DC) is one of serious complications of diabetic patients. This study investigated the biological function of activating transcription factor 4 (ATF4) in DC. Methods and results Streptozotocin‐treated mice and high glucose (HG)‐exposed HL‐1 cells were used as th...

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Bibliographic Details
Main Authors: Yu Li, Qian He, Chao‐Yong He, Chao Cai, Zhen Chen, Jing‐Zhu Duan
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:ESC Heart Failure
Subjects:
ATF4
Diabetic cardiomyopathy
Fibrosis
HIPK2
Oxidative stress
Smurf2
Online Access:https://doi.org/10.1002/ehf2.14404

Internet

https://doi.org/10.1002/ehf2.14404

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