Zebrafish ELL-associated factors Eaf1/2 modulate erythropoiesis via regulating gata1a expression and WNT signaling to facilitate hypoxia tolerance

Zebrafish ELL-associated factors Eaf1/2 modulate erythropoiesis via regulating gata1a expression and WNT signaling to facilitate hypoxia tolerance

Abstract EAF1 and EAF2, the eleven-nineteen lysine-rich leukemia (ELL)-associated factors which can assemble to the super elongation complex (AFF1/4, AF9/ENL, ELL, and P-TEFb), are reported to participate in RNA polymerase II to actively regulate a variety of biological processes, including leukemia...

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Bibliographic Details
Main Authors: WenYe Liu, ShuHui Lin, LingYa Li, ZhiPeng Tai, Jing-Xia Liu
Format: Article
Language:English
Published: SpringerOpen 2023-04-01
Series:Cell Regeneration
Subjects:
EAF1/2
gata1a/scl/lmo2
Erythropoiesis
H3K27me3
WNT/β-Catenin signaling
TCF4
Online Access:https://doi.org/10.1186/s13619-022-00154-3

Internet

https://doi.org/10.1186/s13619-022-00154-3

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