Lactylated Histone H3K18 as a Potential Biomarker for the Diagnosis and Predicting the Severity of Septic Shock

Lactylated Histone H3K18 as a Potential Biomarker for the Diagnosis and Predicting the Severity of Septic Shock

ObjectiveTo date, there are no studies regarding the lactylation profile and its role in critically ill patients. Thus, we aimed to examine expression of histone H3 lysine 18 (H3K18) lactylation and its role in patients with septic shock.MethodsThirteen healthy volunteers and 35 critically ill patie...

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Bibliographic Details
Main Authors: Xin Chu, Chenyi Di, Panpan Chang, Lina Li, Zhe Feng, Shirou Xiao, Xiaoyu Yan, Xiaodong Xu, Hexin Li, Ruomei Qi, Huan Gong, Yanyang Zhao, Fei Xiao, Zhigang Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
septic shock
critical illness
histone
lactylation
H3K18
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.786666/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.786666/full

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