Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) Nef enhances virus replication and contributes to immune evasion in vivo, but the underlying molecular mechanisms remain incompletely defined. Nef interferes with host cell actin dynamics to restrict T lymphocyte responses to chemokine stimulation...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2015-10-01
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| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.01309-15 |