GCK exonic mutations induce abnormal biochemical activities and result in GCK-MODY

GCK exonic mutations induce abnormal biochemical activities and result in GCK-MODY

Objective: Glucokinase-maturity-onset diabetes of the young (GCK-MODY; MODY2) is a rare genetic disorder caused by mutations in the glucokinase (GCK) gene. It is often under- or misdiagnosed in clinical practice, but correct diagnosis can be facilitated by genetic testing. In this study, we examined...

Полное описание

Библиографические подробности
Главные авторы: Tongtong Dai, Yun Yang, Juanjuan Zhang, Xiaoyu Ma, Lifen Chen, Caiping Zhang, Sheng Lv, Lin Li, Renqiao Tang, Ni Zhen, Wenli Lu, Chuanyin Li, Ronggui Hu, Yuan Xiao, Zhiya Dong
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2023-04-01
Серии:Frontiers in Genetics
Предметы:
glucokinase
GCK
gene variants
biochemical activity
GCK-MODY
Online-ссылка:https://www.frontiersin.org/articles/10.3389/fgene.2023.1120153/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1120153/full

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