CGINet: graph convolutional network-based model for identifying chemical-gene interaction in an integrated multi-relational graph

Abstract Background Elucidation of interactive relation between chemicals and genes is of key relevance not only for discovering new drug leads in drug development but also for repositioning existing drugs to novel therapeutic targets. Recently, biological network-based approaches have been proven t...

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Bibliographic Details
Main Authors: Wei Wang, Xi Yang, Chengkun Wu, Canqun Yang
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-03899-3