Modifier effects between regulatory and protein-coding variation.

Modifier effects between regulatory and protein-coding variation.

Genome-wide associations have shown a lot of promise in dissecting the genetics of complex traits in humans with single variants, yet a large fraction of the genetic effects is still unaccounted for. Analyzing genetic interactions between variants (epistasis) is one of the potential ways forward. We...

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Bibliographic Details
Main Authors: Antigone S Dimas, Barbara E Stranger, Claude Beazley, Robert D Finn, Catherine E Ingle, Matthew S Forrest, Matthew E Ritchie, Panos Deloukas, Simon Tavaré, Emmanouil T Dermitzakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2570624?pdf=render

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http://europepmc.org/articles/PMC2570624?pdf=render

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