L-Ascorbic Acid 2-Phosphate Attenuates Methylmercury-Induced Apoptosis by Inhibiting Reactive Oxygen Species Accumulation and DNA Damage in Human SH-SY5Y Cells

L-Ascorbic Acid 2-Phosphate Attenuates Methylmercury-Induced Apoptosis by Inhibiting Reactive Oxygen Species Accumulation and DNA Damage in Human SH-SY5Y Cells

Methylmercury (MeHg) is a toxin that causes severe neuronal oxidative damage. As vitamin C is an antioxidant well-known to protect neurons from oxidative damage, our goal was to elucidate its protective mechanism against MeHg-induced oxidative stress in human neuroblastomas (SHSY5Y). We treated cell...

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Bibliographic Details
Main Authors: Kuiyang Zuo, Qi Xu, Yujie Wang, Yutong Sui, Ye Niu, Zinan Liu, Mingsheng Liu, Xinpeng Liu, Dan Liu, Wei Sun, Ziyu Wang, Xiaomei Liu, Jinyu Liu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Toxics
Subjects:
methylmercury
reactive oxygen species
DNA damage
DNA repair
apoptosis
AA2P
Online Access:https://www.mdpi.com/2305-6304/11/2/144

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https://www.mdpi.com/2305-6304/11/2/144

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