P435 HER2/neu-derived peptide conjugated to liposomes containing DOPE as an effective prophylactic vaccine formulation for breast cancer

P435 HER2/neu-derived peptide conjugated to liposomes containing DOPE as an effective prophylactic vaccine formulation for breast cancer

The present study was aimed to develop an effective nanoliposomal vaccine delivery system with P435 HER2/neu-derived peptide conjugated to Maleimide-PEG2000-DSPE. The nanoliposome formulation composed of DSPC/DSPG/Chol/DOPE and monophosphoryl lipid A was used as an adjuvant. Liposomal formulations w...

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Bibliographic Details
Main Authors: Niloofar Farzad, Nastaran Barati, Amir Abbas Momtazi-Borojeni, Mona Yazdani, Atefeh Arab, Atefeh Razazan, Sheida Shariat, Mercedeh Mansourian, Azam Abbasi, Zahra Saberi, Ali Badiee, Seyed Amir Jalali, Mahmoud Reza Jaafari
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Peptide-conjugated nanoliposomes
P435 peptide
prophylactic vaccine
cytotoxic T-cell response
HER2/neu protein
breast cancer
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2019.1576702

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https://www.tandfonline.com/doi/10.1080/21691401.2019.1576702

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