Identification and genetic engineering of pneumococcal capsule-like polysaccharides in commensal oral streptococci

Identification and genetic engineering of pneumococcal capsule-like polysaccharides in commensal oral streptococci

ABSTRACTCapsular polysaccharides (CPS) in Streptococcus pneumoniae are pivotal for bacterial virulence and present extensive diversity. While oral streptococci show pronounced antigenicity toward pneumococcal capsule-specific sera, insights into evolution of capsule diversity remain limited. This st...

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Bibliographic Details
Main Authors: Ren Wu, Moon Nahm, Jinghua Yang, C. Allen Bush, Hui Wu
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
Streptococcus parasanguinis
capsular polysaccharides
pneumococcal capsule
serotype switching
genetic engineering
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01885-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01885-23

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