Enantioselective Michael/Hemiketalization Cascade Reactions between Hydroxymaleimides and 2-Hydroxynitrostyrenes for the Construction of Chiral Chroman-Fused Pyrrolidinediones

Enantioselective Michael/Hemiketalization Cascade Reactions between Hydroxymaleimides and 2-Hydroxynitrostyrenes for the Construction of Chiral Chroman-Fused Pyrrolidinediones

In this paper, the organocatalytic asymmetric Michael addition/hemiketalization cascade reactions between hydroxymaleimides and 2-hydroxynitrostyrenes were developed, which provided a new protocol for building a chiral ring-fused chroman skeleton. This squaramide-catalyzed cascade reaction provided...

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Bibliographic Details
Main Authors: Dong-Hua Xie, Cheng Niu, Da-Ming Du
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Molecules
Subjects:
organocatalysis
asymmetric catalysis
cascade reaction
hydroxymaleimide
chroman
pyrrolidinedione
Online Access:https://www.mdpi.com/1420-3049/27/16/5081

Internet

https://www.mdpi.com/1420-3049/27/16/5081

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