trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans

trim-21 promotes proteasomal degradation of CED-1 for apoptotic cell clearance in C. elegans

The phagocytic receptor CED-1 mediates apoptotic cell recognition by phagocytic cells, enabling cell corpse clearance in Caenorhabditis elegans. Whether appropriate levels of CED-1 are maintained for executing the engulfment function remains unknown. Here, we identified the C. elegans E3 ubiquitin l...

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Bibliographic Details
Main Authors: Lei Yuan, Peiyao Li, Huiru Jing, Qian Zheng, Hui Xiao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
apoptosis
apoptotic cell clearance
phagocytic receptor
E3 ubiquitin ligase
phagosome
Online Access:https://elifesciences.org/articles/76436

Internet

https://elifesciences.org/articles/76436

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