New Library of Iodo-Quinoline Derivatives Obtained by an Alternative Synthetic Pathway and Their Antimicrobial Activity

New Library of Iodo-Quinoline Derivatives Obtained by an Alternative Synthetic Pathway and Their Antimicrobial Activity

6-Iodo-substituted carboxy-quinolines were obtained using a one-pot, three-component method with trifluoroacetic acid as a catalyst under acidic conditions. Iodo-aniline, pyruvic acid and 22 phenyl-substituted aldehydes (we varied the type and number of radicals) or O-heterocycles, resulting in diff...

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Bibliographic Details
Main Authors: Cristina Maria Al-Matarneh, Alina Nicolescu, Ioana Cristina Marinaş, Mădalina Diana Găboreanu, Sergiu Shova, Andrei Dascălu, Mihaela Silion, Mariana Pinteală
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molecules
Subjects:
iodo-quinolines
Doebner synthesis
antimicrobial activity
<i>S. epidermidis</i>
<i>K. pneumonie</i>
<i>C. parapsilosis</i>
Online Access:https://www.mdpi.com/1420-3049/29/4/772

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https://www.mdpi.com/1420-3049/29/4/772

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