Baseline JAK phosphorylation profile of peripheral blood leukocytes, studied by whole blood phosphospecific flow cytometry, is associated with 1-year treatment response in early rheumatoid arthritis

Baseline JAK phosphorylation profile of peripheral blood leukocytes, studied by whole blood phosphospecific flow cytometry, is associated with 1-year treatment response in early rheumatoid arthritis

Abstract Background We found recently that baseline signal transducer and activator of transcription 3 phosphorylation in peripheral blood CD4+ T cells of patients with early rheumatoid arthritis (RA) is associated with treatment response to synthetic disease-modifying antirheumatic drugs (DMARDs)....

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Bibliographic Details
Main Authors: Krista Kuuliala, Antti Kuuliala, Riitta Koivuniemi, Hannu Kautiainen, Heikki Repo, Marjatta Leirisalo-Repo
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Arthritis Research & Therapy
Subjects:
Rheumatoid arthritis
Disease-modifying antirheumatic drug
Janus kinases
Phosphorylation
Blood
Leukocyte
Online Access:http://link.springer.com/article/10.1186/s13075-017-1278-0

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http://link.springer.com/article/10.1186/s13075-017-1278-0

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