First Responders to Hyperosmotic Stress in Murine Astrocytes: Connexin 43 Gap Junctions Are Subject to an Immediate Ultrastructural Reorganization

First Responders to Hyperosmotic Stress in Murine Astrocytes: Connexin 43 Gap Junctions Are Subject to an Immediate Ultrastructural Reorganization

In a short-term model of hyperosmotic stress, primary murine astrocytes were stimulated with a hyperosmolar sucrose solution for five minutes. Astrocytic gap junctions, which are mainly composed of Connexin (Cx) 43, displayed immediate ultrastructural changes, demonstrated by freeze–fracture replica...

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Bibliographic Details
Main Authors: Anja Beckmann, Johanna Recktenwald, Alice Ferdinand, Alexander Grißmer, Carola Meier
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biology
Subjects:
FRIL
Cx43
sucrose
hyperosmolar
freeze fracture
ultrastructure
Online Access:https://www.mdpi.com/2079-7737/10/12/1307

Internet

https://www.mdpi.com/2079-7737/10/12/1307

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