Effect of Aggregated β-Amyloid (1-42) on Synaptic Plasticity of Hippocampal Dentate Gyrus Granule Cells in Vivo
Introduction: Alzheimer’s disease (AD) is a common neurodegenerative disorder in elderly people with an impairment of cognitive decline and memory loss. β-amyloid (Aβ) as a potent neurotoxic peptide has a pivotal role in the pathogenesis of AD. This disease begins with impairment in synaptic functio...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2012-12-01
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Series: | BioImpacts |
Subjects: | |
Online Access: | http://dx.doi.org/10.5681/bi.2012.022 |