Effects of recombinant human soluble thrombomodulin on neutrophil extracellular traps in the kidney of a mouse model of endotoxin shock

Effects of recombinant human soluble thrombomodulin on neutrophil extracellular traps in the kidney of a mouse model of endotoxin shock

Objectives: Sepsis is a life-threatening condition characterized by multi-organ dysfunction due to host immune system dysregulation in response to an infection. During sepsis, neutrophils release neutrophil extracellular traps (NETs) as part of the innate immune response. However, excessive NETs pla...

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Bibliographic Details
Main Authors: Tatsuhiko Harada, Yasuyo Shimomura, Osamu Nishida, Munenori Maeda, Yu Kato, Tomoyuki Nakamura, Naohide Kuriyama, Hidefumi Komura
Format: Article
Language:English
Published: Fujita Medical Society 2023-08-01
Series:Fujita Medical Journal
Subjects:
neutrophil extracellular trap
sepsis
thrombomodulin
lipopolysaccharide
kidney
Online Access:https://www.jstage.jst.go.jp/article/fmj/9/3/9_2022-026/_pdf/-char/en

Internet

https://www.jstage.jst.go.jp/article/fmj/9/3/9_2022-026/_pdf/-char/en

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