Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine

Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine

Recent pharmacological studies indicated that the modulation of tripartite-synaptic transmission plays important roles in the pathophysiology of schizophrenia, mood disorders and adverse reactions. Therefore, to explore the mechanisms underlying the clinical and adverse reactions to atypical antipsy...

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Bibliographic Details
Main Authors: Motohiro Okada, Kouji Fukuyama, Eishi Motomura
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Akt
AMPK
astrocyte
connexin43
D-serine
Erk
Online Access:https://www.mdpi.com/1422-0067/23/16/9103

Internet

https://www.mdpi.com/1422-0067/23/16/9103

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