Different CprABC amino acid sequences affect nisin A susceptibility in Clostridioides difficile isolates.

Clinical isolates of Clostridioides difficile sometimes exhibit multidrug resistance and cause diarrhea after antibiotic administration. Metronidazole and vancomycin are often used as therapeutic agents, but resistance to these antibiotics has been found clinically. Therefore, the development of alt...

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Bibliographic Details
Main Authors: Noriaki Ide, Miki Kawada-Matsuo, Mi Nguyen-Tra Le, Junzo Hisatsune, Hiromi Nishi, Toshinori Hara, Norikazu Kitamura, Seiya Kashiyama, Michiya Yokozaki, Hiroyuki Kawaguchi, Hiroki Ohge, Motoyuki Sugai, Hitoshi Komatsuzawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0280676