Synthesis of Quinoxalin-2(1H)-ones and Hexahydroquinoxalin-2(1H)-ones via Oxidative Amidation–Heterocycloannulation

Synthesis of Quinoxalin-2(1H)-ones and Hexahydroquinoxalin-2(1H)-ones via Oxidative Amidation–Heterocycloannulation

Abstract A metal-catalyst-free synthesis of substituted quinoxalin-2-ones from 2,2-dibromo-1-arylethanone by employing an oxidative amidation–heterocycloannulation protocol is reported. The substrate scope of the reaction has been demonstrated and a possible mechanism for this reaction has also been...

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Bibliographic Details
Main Authors: Akula Raghunadh, Krishnaji Tadiparthi, Suresh Babu Meruva, V. Narayana Murthy, L. Vaikunta Rao, U. K. Syam Kumar
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2020-07-01
Series:SynOpen
Subjects:
oxidative amidation
heterocycloannulation
quinoxalin-2(1h)-one
2,2-dibromo-1-arylethanone
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1707203

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1707203

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