SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells

SUMOylation modulates eIF5A activities in both yeast and pancreatic ductal adenocarcinoma cells

Abstract Background The eukaryotic translation initiation protein eIF5A is a highly conserved and essential factor that plays a critical role in different physiological and pathological processes including stress response and cancer. Different proteomic studies suggest that eIF5A may be a small ubiq...

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Main Authors: Rocío Seoane, Tomás Lama-Díaz, Antonia María Romero, Ahmed El Motiam, Arantxa Martínez-Férriz, Santiago Vidal, Yanis H. Bouzaher, María Blanquer, Rocío M. Tolosa, Juan Castillo Mewa, Manuel S. Rodríguez, Adolfo García-Sastre, Dimitris Xirodimas, James D. Sutherland, Rosa Barrio, Paula Alepuz, Miguel G. Blanco, Rosa Farràs, Carmen Rivas
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cellular & Molecular Biology Letters
Subjects:
eIF5A
Pancreatic ductal adenocarcinoma
Stress granules
Stress response
SUMO2
Online Access:https://doi.org/10.1186/s11658-024-00533-5

Internet

https://doi.org/10.1186/s11658-024-00533-5

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