The stringent response and cell cycle arrest in Escherichia coli.

The bacterial stringent response, triggered by nutritional deprivation, causes an accumulation of the signaling nucleotides pppGpp and ppGpp. We characterize the replication arrest that occurs during the stringent response in Escherichia coli. Wild type cells undergo a RelA-dependent arrest after tr...

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Bibliographic Details
Main Authors: Daniel J Ferullo, Susan T Lovett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2586660?pdf=render