Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England.

Genetic drift in infectious disease transmission results from randomness of transmission and host recovery or death. The strength of genetic drift for SARS-CoV-2 transmission is expected to be high due to high levels of superspreading, and this is expected to substantially impact disease epidemiolog...

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Bibliographic Details
Main Authors: QinQin Yu, Joao A Ascensao, Takashi Okada, COVID-19 Genomics UK (COG-UK) Consortium, Olivia Boyd, Erik Volz, Oskar Hallatschek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-04-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1012090&type=printable