Evaluation of the Influence of <i>CYP2C9* 2, CYP2C9*3</i> Gene Polymorphisms on the Efficacy and Safety of Postoperative Analgesia with Ketoprofen in Patients after Cardiac Surgery

Evaluation of the Influence of <i>CYP2C9* 2, CYP2C9*3</i> Gene Polymorphisms on the Efficacy and Safety of Postoperative Analgesia with Ketoprofen in Patients after Cardiac Surgery

Aim. The aim of the study was to evaluate the efficacy and safety of ketoprofen as an analgesic therapy in patients with CYP2C9*2 (430C&gt;T) rs179985 and CYP2C9*3 (1075A&gt;C) rs1057910 gene polymorphisms after cardiac surgery.Material and methods. The study included 90 patients. Postoperat...

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Bibliographic Details
Main Authors: T. E. Morozova, D. A. Shatsky, N. V. Shikh, E. V. Shikh, T. B. Andrushchyshina, M. V. Lukina, A. A. Kachanova, Zh. A. Sozaeva, G. N. Shuev, N. P. Denisenko, E. A. Grishina, D. A. Sychev
Format: Article
Language:English
Published: Столичная издательская компания 2021-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
postoperative analgesia
cardiac surgery
pharmacogenetics
acute kidney injury
ketoprofen
Online Access:https://www.rpcardio.online/jour/article/view/2539

Internet

https://www.rpcardio.online/jour/article/view/2539

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