The role of ferroptosis in intervertebral disc degeneration

The role of ferroptosis in intervertebral disc degeneration

Nucleus pulposus, annulus fibrosus, and cartilage endplate constitute an avascular intervertebral disc (IVD), which is crucial for spinal and intervertebral joint mobility. As one of the most widespread health issues worldwide, intervertebral disc degeneration (IVDD) is recognized as a key contribut...

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Bibliographic Details
Main Authors: Chunyang Fan, Genglei Chu, Zilin Yu, Zhongwei Ji, Fanchen Kong, Lingye Yao, Jiale Wang, Dechun Geng, Xiexing Wu, Haiqing Mao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
intervertebral disc degeneration
ferroptosis
lipid peroxidation
antioxidant system
reactive oxygen species
epigenetics
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1219840/full

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https://www.frontiersin.org/articles/10.3389/fcell.2023.1219840/full

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