Microbiota-derived tryptophan metabolism: Impacts on health, aging, and disease

The intricate interplay between gut microbiota and the host is pivotal in maintaining homeostasis and health. Dietary tryptophan (TRP) metabolism initiates a cascade of essential endogenous metabolites, including kynurenine, kynurenic acid, serotonin, and melatonin, as well as microbiota-derived Trp...

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Bibliographic Details
Main Authors: Sonu Kumar Gupta, Sagar Vyavahare, Ian L. Duchesne Blanes, Ford Berger, Carlos Isales, Sadanand Fulzele
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Experimental Gerontology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556523002401