Pioneer Use of Antimalarial Transdermal Combination Therapy in Rodent Malaria Model

Pioneer Use of Antimalarial Transdermal Combination Therapy in Rodent Malaria Model

We have previously reported 1,2,6,7-tetraoxaspiro [7.11]nonadecane (N-89) as a promising antimalarial compound. In this study, we evaluated the effect of transdermal therapy (tdt) of N-89 in combination (tdct) with other antimalarials as an application for children. We prepared ointment formulas con...

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Bibliographic Details
Main Authors: Nagwa S. M. Aly, Hiroaki Matsumori, Thi Quyen Dinh, Akira Sato, Shin-Ichi Miyoshi, Kyung-Soo Chang, Hak Sun Yu, Duc Tuan Cao, Hye-Sook Kim
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pathogens
Subjects:
transdermal N-89
mefloquine
pyrimethamine
antimalarials
combination
in vivo
Online Access:https://www.mdpi.com/2076-0817/12/3/398

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https://www.mdpi.com/2076-0817/12/3/398

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