Late Inflammation Induced by Asbestiform Fibers in Mice Is Ameliorated by a Small Molecule Synthetic Lignan

Late Inflammation Induced by Asbestiform Fibers in Mice Is Ameliorated by a Small Molecule Synthetic Lignan

Exposure to Libby amphibole (LA) asbestos-like fibers is associated with increased risk of asbestosis, mesothelioma, pulmonary disease, and systemic autoimmune disease. LGM2605 is a small molecule antioxidant and free radical scavenger, with anti-inflammatory effects in various disease models. The c...

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Bibliographic Details
Main Authors: Reagan Badger, Kyewon Park, Ralph A. Pietrofesa, Melpo Christofidou-Solomidou, Kinta M. Serve
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
asbestiform fibers
asbestos
autoimmunity
inflammation
LGM2605
Libby amphibole
Online Access:https://www.mdpi.com/1422-0067/22/20/10982

Internet

https://www.mdpi.com/1422-0067/22/20/10982

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