Transient deoxyhemoglobin formation as a contrast for perfusion MRI studies in patients with brain tumors: a feasibility study

Transient deoxyhemoglobin formation as a contrast for perfusion MRI studies in patients with brain tumors: a feasibility study

Background: Transient hypoxia-induced deoxyhemoglobin (dOHb) has recently been shown to represent a comparable contrast to gadolinium-based contrast agents for generating resting perfusion measures in healthy subjects. Here, we investigate the feasibility of translating this non-invasive approach to...

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Bibliographic Details
Main Authors: Vittorio Stumpo, Ece Su Sayin, Jacopo Bellomo, Olivia Sobczyk, Christiaan Hendrik Bas van Niftrik, Martina Sebök, Michael Weller, Luca Regli, Zsolt Kulcsár, Athina Pangalu, Andrea Bink, James Duffin, David D. Mikulis, Joseph A. Fisher, Jorn Fierstra
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Physiology
Subjects:
MR perfusion
deoxyhemoglobin
brain tumor
glioblastoma
advanced imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2024.1238533/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2024.1238533/full

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