Type I Interferons Enhance the Repair of Ultraviolet Radiation-Induced DNA Damage and Regulate Cutaneous Immune Suppression

Type I Interferons Enhance the Repair of Ultraviolet Radiation-Induced DNA Damage and Regulate Cutaneous Immune Suppression

Type I interferons (IFNs) are important enhancers of immune responses which are downregulated in human cancers, including skin cancer. Solar ultraviolet (UV) B radiation is a proven environmental carcinogen, and its exposure contributes to the high prevalence of skin cancer. The carcinogenic effects...

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Bibliographic Details
Main Authors: Mohammad Asif Sherwani, Israr Ahmad, Monica J. Lewis, Ahmed Abdelgawad, Harunur Rashid, Kevin Yang, Ching-Yi Chen, Chander Raman, Craig A. Elmets, Nabiha Yusuf
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
ultraviolet radiation
type I interferons
skin
DNA repair
immune suppression
Online Access:https://www.mdpi.com/1422-0067/23/3/1822

Internet

https://www.mdpi.com/1422-0067/23/3/1822

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