Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Spinal cord injury reprograms muscle fibroadipogenic progenitors to form heterotopic bones within muscles

Abstract The cells of origin of neurogenic heterotopic ossifications (NHOs), which develop frequently in the periarticular muscles following spinal cord injuries (SCIs) and traumatic brain injuries, remain unclear because skeletal muscle harbors two progenitor cell populations: satellite cells (SCs)...

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Bibliographic Details
Main Authors: Hsu-Wen Tseng, Dorothée Girard, Kylie A. Alexander, Susan M. Millard, Frédéric Torossian, Adrienne Anginot, Whitney Fleming, Jules Gueguen, Marie-Emmanuelle Goriot, Denis Clay, Beulah Jose, Bianca Nowlan, Allison R. Pettit, Marjorie Salga, François Genêt, Marie-Caroline Le Bousse-Kerdilès, Sébastien Banzet, Jean-Pierre Lévesque
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-022-00188-y

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https://doi.org/10.1038/s41413-022-00188-y

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