Insulin Regulates GABAA Receptor-Mediated Tonic Currents in the Prefrontal Cortex

Insulin Regulates GABAA Receptor-Mediated Tonic Currents in the Prefrontal Cortex

Recent studies, have shown that insulin increases extrasynaptic GABAA receptor-mediated currents in the hippocampus, causing alterations of neuronal excitability. The prefrontal cortex (PFC) is another brain area which is involved in cognition functions and expresses insulin receptors. Here, we used...

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Bibliographic Details
Main Authors: Saraí Trujeque-Ramos, Diego Castillo-Rolón, Elvira Galarraga, Dagoberto Tapia, Gabina Arenas-López, Stefan Mihailescu, Salvador Hernández-López
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neuroscience
Subjects:
extrasynaptic GABAA receptors
ambient GABA
receptor trafficking
brain slices
neuronal excitability
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00345/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00345/full

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