Lead Induces Apoptosis and Histone Hyperacetylation in Rat Cardiovascular Tissues.

Acute and chronic lead (Pb) exposure might cause hypertension and cardiovascular diseases. The purpose of this study was to evaluate the effects of early acute exposure to Pb on the cellular morphology, apoptosis, and proliferation in rats and to elucidate the early mechanisms involved in the develo...

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Bibliographic Details
Main Authors: Li-Hui Xu, Fang-Fang Mu, Jian-Hong Zhao, Qiang He, Cui-Li Cao, Hui Yang, Qi Liu, Xue-Hui Liu, Su-Ju Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0129091