Protective Effects of Clenbuterol against Dexamethasone-Induced Masseter Muscle Atrophy and Myosin Heavy Chain Transition.

Glucocorticoid has a direct catabolic effect on skeletal muscle, leading to muscle atrophy, but no effective pharmacotherapy is available. We reported that clenbuterol (CB) induced masseter muscle hypertrophy and slow-to-fast myosin heavy chain (MHC) isoform transition through direct muscle β2-adren...

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Bibliographic Details
Main Authors: Daisuke Umeki, Yoshiki Ohnuki, Yasumasa Mototani, Kouichi Shiozawa, Kenji Suita, Takayuki Fujita, Yoshiki Nakamura, Yasutake Saeki, Satoshi Okumura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4460071?pdf=render